Nebilet Plus contains nebivolol and hydrochlorothiazide as the active ingredients. Nebivolol is a cardiovascular drug belonging to the group of selective beta-blocking agents (i.e. with a selective action on the cardiovascular system). It prevents increased heart rate and controls heart pumping strength. It also widens blood vessels, which helps to lower your blood pressure. Hydrochlorothiazide is a diuretic, that acts by increasing the amount of urine you produce. Nebilet Plus is a one-tablet combination of nebivolol and hydrochlorothiazlde and is used for the treatment of raised blood pressure (hypertension). It is used instead of the two separate products for those patients who are already taking them together.